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Advances MGD011 into Phase I development
July 28, 2015
By: Kristin Brooks
Managing Editor, Contract Pharma
MacroGenics, Inc. has initiated dosing in a Phase I trial of MGD011 (also known as JNJ-64052781), triggering a $10 million milestone payment from partner Janssen Biotech. MGD011 incorporates MacroGenics’ platform for Dual-Affinity Re-Targeting (DART) to simultaneously target CD19 and CD3 for the potential treatment of B-cell malignancies. The Phase I trial will evaluate the safety, tolerability and preliminary clinical activity of MGD011 when administered to patients with relapsed or refra...
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